一、基本信息
毛志强，教授，博士生导师，省级人才
研究领域：荧光探针与活体成像、重大疾病的分子诊疗
电子邮件：maozq@hubu.edu.cn
二、教育背景及工作经历
2024.10—至今 威廉希尔中国官网 威廉williamhill官网，教授
2022.3—2023.3 韩国高丽大学(Korea University) 化学系，访问学者
2019.7-2024.9 威廉希尔中国官网化学化工学院、威廉williamhill官网，副教授
2018.2—2019.6 威廉希尔中国官网 化学化工学院，讲师
2017.7—2018.1 中南民族大学，研究助理
2012.9—2017.6 武汉大学，博士，分析化学
三、研究方向
主要研究方向包括近红外分子荧光探针的研制及活体成像分析，涉及脑疾病的分子影像、肿瘤联合治疗等领域，主持国家自然科学基金项目2项、湖北省自然科学基金项目1项，以第一作者/通讯作者在Nat. Commun.(1篇),Angew. Chem. Int. Ed.(2篇),Matter(1篇),Adv. Funct. Mater.(1篇）,AdvancedScience(1篇）,Coordination Chemistry Reviews(4篇),Analytical Chemistry(5篇),Chemical Science(3篇),J. Hazard. Mater.(1篇)等国际学术刊物发表SCI论文40余篇，教学研究论文2篇，申请专利5项；长期应邀担任Advanced Materials,ChemicalScience,AnalyticalChemistry等期刊论文审稿人，担任Journal of Analysis and Testing等学术期刊青年编委。
四、科研项目
1.国家自然科学基金面上项目，项目批准号：22174034，2022-01至2025-12，主持。
2.国家自然科学基金青年项目，项目批准号：21804033，2019-01至2021-12，主持。
3.湖北省自然科学基金面上项目，项目批准号：2021CFB305，2021-10至2023-09，主持。
五、代表性论文
1.Miantai Ye, Xiaoyu Wang, Jingwen Zou, Wei Sun, Weijie Chi,*Zhiqiang Mao,* Zhihong Liu,* Breaking shackles of molecular weight and emission for NIR-II fluorophores by regulating Columb attraction interaction,Nature Communications, 2025, 16, 8007. (SCI一区，IF=15.7)
2.Jiankang Gong, Xiaoyu Wang, Jiao Wu, Changyu Yoon, Yujin Kim, Jingwen Zou,Zhiqiang Mao,*Jong Seung Kim,*Diaminonaphthalene Boronic Acid (DANBA): New Approach for Peroxynitrite Sensing Site.Angew. Chem. Int. Ed. 2024,63,e202409295. (SCI一区，IF=16.1)
3.Pengzhang Wang, Le Yu, Jiankang Gong, Jianhua Xiong, Soyu Zi, Hua Xie, Fan Zhang,Zhiqiang Mao,* Zhihong Liu,* Jong Seung Kim.* An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain.Angew. Chem. Int. Ed.2022,61,e202206894. (SCI一区，IF=16.823)
4.Jianhua Xiong, Pengzhan Wang, Subin Son, Zhong Cheng, Fan Zhang,Zhiqiang Mao,* Zhihong Liu,* Jong Seung Kim.* Engineering a theranostic platform for synergistic hypoxia-responsive photodynamic therapy and chemotherapy.Matter2022, 5, 1502-1519. (SCI一区, IF=19.967)
5.Zhiqiang Mao, Hyeonji Rha, Jungryun Kim, Xinru You, Fan Zhang,*Wei Tao,*Jong Seung Kim.*THQ–Xanthene: An Emerging Strategy to Create Next-Generation NIR-I/II Fluorophores.Advanced Science, 2023, 10, 2301177. (SCI一区, IF=17.521)
6.Jianhua Xiong, Xiaoyu Wang, Jaewon Kim, Jiankang Gong,Zhiqiang Mao,* Jong Seung Kim,* Zhihong Liu.* Tumor-Activated Prodrug with Synergistic Anti-Stemness Chemical and Photodynamic Therapies.Advanced Functional Materials, 2024, 34，2312590. (SCI一区，IF=19.0)
7.Xiaoyu Wang, Weijie Chi,* Jiao Wu, Jingwen Zou, Jiyoung Yoo, Seokjin Hong, Fan Zhang,Zhiqiang Mao,* Jong Seung Kim,* A NIR-II emissive sonosensitized biotuner for pyroptosis-enhanced sonodynamic therapy of hypoxic tumors.Biomaterials, 2025, 315, 122969.(SCI一区，IF=12.9)
8.Jianhua Xiong, Weijie Chi, Miantai Ye, Li Zhang, Xiaoyu Wang,Zhiqiang Mao,* and Zhihong Liu.* Activatable Phototherapeutic Prodrug Conquering Hypoxia Limitation to Enhance Chemical Drug Delivery Efficiency.ACS Materials Letters2024, 6, 2548−2558. (SCI一区，IF=11.4)
9.Zhiqiang Mao, Jianhua Xiong, Pengzhan Wang, Jusung An, Fan Zhang, Zhihong Liu,* Jong Seung Kim.* Activity-based fluorescence probes for pathophysiological peroxynitrite fluxes.Coordination Chemistry Reviews2022, 454, 214356. (SCI一区，IF=24.833)
10.Zhiqiang Mao, Ji Hyeon Kim, Jieun Lee, Hao Xiong, Fan Zhang,* Jong Seung Kim.* Engineering of BODIPY-based theranostics for cancer therapy,Coordination Chemistry Reviews2023, 476, 214908. (SCI一区，IF=24.833)
11.Xiaoyu Wang, Jiankang Gong, Jiaxuan Wang, Fan Zhang,Zhiqiang Mao*, Zhihong Liu*. Engineering molecular theranostic probes for antibaterial therapy.Trends in Analytical Chemistry, 2023, 167, 117232. (SCI一区， IF=13.1)
12.Maintai Ye, Yunhui Xiang, Jiankang Gong, Xiaoyu Wang,Zhiqiang Mao,* Zhihong Liu.* Monitoring Hg2+and MeHg+Poisoning in Living Body with An Activatable Near-infrared II Fluorescence Probe,Journal of Hazardous Materials, 2023, 445, 130612. (SCI一区，IF=14.224)
13.Songjiao Li, Peipei Wang, Miantai Ye, Ke Yang, Dan Cheng,Zhiqiang Mao*, Longwei He*, and Zhihong Liu. Cysteine-Activatable Near-Infrared Fluorescent Probe for Dual-Channel Tracking Lipid Droplets and Mitochondria in Epilepsy.Analytical Chemistry, 2023, 95, 5133–5141.(SCI一区，IF=8.008)
14.Pengzhan Wang, Xianhua Cheng, Jianhua Xiong,Zhiqiang Mao,* Zhihong Liu.* Revealing Formaldehyde Fluxes in Alzheimer's Disease Brain by an Activity-Based Fluorescence Probe.Chinese Journal of Chemistry2022, 40, 1457-1463. (SCI二区，IF=5.560)
15.Zhao Wang, Weiwei Wang, Pengzhan Wang,Zhiqiang Mao,* Zhihong Liu.* Highly Sensitive Near-Infrared Imaging of Peroxynitrite Fluxes in Inflammation Progress.Analytical Chemistry2021, 93, 3035-3041.(SCI一区，IF=6.986)
16.Weiwei Wang, Jianhua Xiong, Xinjian Song, Zhao Wang, Fan Zhang,Zhiqiang Mao.* Activatable Two-Photon Near-Infrared Fluorescent Probe Tailored toward Peroxynitrite In Vivo Imaging in Tumors.Analytical Chemistry2020, 92, 13305-13312. (SCI一区，IF=6.785)
17.Jianhua Xiong, Weiwei Wang, Caixia Wang, Cheng Zhong, Renqiang Ruan,Zhiqiang Mao*, Zhihong Liu.* Visualizing Peroxynitrite in Microvessels of the Brain with Stroke Using an Engineered Highly Specific Fluorescent Probe.ACS Sensors2020, 5, 3237-3245. (SCI一区，IF=7.333)
18.Yan Lou, Caixia Wang, Siyu Chi, Songjiao Li,Zhiqiang Mao* and Zhihong Liu.* Construction of a two-photon fluorescent probe for ratiometric imaging of hypochlorous acid in alcohol-induced liver injury.Chemical Communications2019, 55, 12912-12915. (SCI一区，IF=6.164)
19.Zhiqiang Mao, Miantai Ye, Wei Hu, Xiaoxue Ye, Yanying Wang, Huijuan Zhang, Chunya Li* and Zhihong Liu.* Design of a ratiometric two-photon probe for imaging of hypochlorous acid (HClO) in wounded tissues.Chemical Science2018, 9, 6035-6040. (SCI一区，IF=9.556)
20.Zhiqiang Mao, Hong Jiang, Xinjian Song, Wei Hu and Zhihong Liu.* Development of a Silicon-Rhodamine Based Near-Infrared Emissive Two-Photon Fluorescent Probe for Nitric Oxide.Analytical Chemistry2017, 89, 9620-9624.(SCI一区，IF=6.042)
21.Zhiqiang Mao, Hong Jiang, Zhen Li, Cheng Zhong, Wei Zhang and Zhihong Liu.* AnN-nitrosation reactivity-based two-photon fluorescent probe for the specific in situ detection of nitric oxide.Chemical Science2017, 8, 4533-4538. (SCI一区，IF=9.063)
22.Zhiqiang Mao, Wenqi Feng, Zhen Li, Lingyu Zeng, Weijie Lv and Zhihong Liu*. NIR in, far-red out: developing a two-photon fluorescent probe for tracking nitric oxide in deep tissue.Chemical Science2016, 7, 5230-5235. (SCI一区，IF=8.668)
23.Zhiqiang Mao, Liang Hu, ChengZhong, Heng Zhang, Bi-Feng Liu* and Zhihong Liu*. A dual-mechanism strategy to design a wide-range pH probe with multicolor fluorescence.Sensor. Actuat. B-Chem. 2015, 219, 179-184.(SCI一区，IF=4.758)
24.Zhiqiang Mao, Liang Hu, Xiaohu Dong, Cheng Zhong, Bi-Feng Liu and Zhihong Liu*.Highly Sensitive Quinoline-Based Two-Photon Fluorescent Probe for Monitoring Intracellular Free Zinc Ions.Analytical Chemistry2014, 86, 6548-6554. (SCI一区，IF=5.825)
